Medical research

Stem cell signal drives new bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to ...

Immunology

Probiotics increase bone volume in healthy mice

A widely-used probiotic stimulates bone formation in young female mice, according to a study published November 13th in the journal Immunity. In response to treatment with Lactobacillus rhamnosus GG (LGG), other intestinal ...

Diseases, Conditions, Syndromes

New mechanism activates bone-building cells in osteoperosis

The number of osteoporosis medications that promote bone formation are few compared to those that suppress bone resorption. A research group led by Kumamoto University scientists has discovered that the gene SIRT7 is important ...

Medical research

The art of building bone

Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...

Medical research

How metal scaffolds enhance the bone healing process

A new study shows how mechanically optimized constructs known as titanium-mesh scaffolds can optimize bone regeneration. The induction of bone regeneration is of importance when treating large bone defects. As demonstrated ...

Diseases, Conditions, Syndromes

Depression, anxiety may affect bone metabolism in older teens

(HealthDay)—Major depressive disorder (MDD), generalized anxiety disorder (GAD), and selective serotonin reuptake inhibitor (SSRI) use are associated with bone metabolism in older adolescents and young adults, according ...

Medical research

Link between cells associated with aging and bone loss

Mayo Clinic researchers have reported a causal link between senescent cells - the cells associated with aging and age-related disease - and bone loss in mice. Targeting these cells led to an increase in bone mass and strength. ...

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Ossification

Ossification is a medical term that is synonymous with bone tissue formation. Endochondral ossification and intramembranous ossification are two processes resulting in the formation of normal, healthy bone tissue. Heterotopic ossification is a process resulting in the formation of bone tissue, that is often atypical, at an extraskeletal location. Calcification is a medical term that is often confused with ossification. Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue. Calcification is a process that occurs during ossification, but not vice versa.

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