Surgery

New strategies for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds. The study design and results are reported ...

Biomedical technology

New filling for bone defects encourages tissue regeneration

A combination of a synthetic material with natural bone fills bone defects and encourages tissue regeneration, with potential for use during surgical procedures. The research was carried out at the Tohoku University Graduate ...

Diseases, Conditions, Syndromes

Serendipity opens new path toward osteoporosis treatment

A cellular protein whose normal function appears to suppress bone formation may be a potential new target for treating osteoporosis, according to a collaborative study led by Weill Cornell Medicine and NewYork-Presbyterian ...

Medical research

Optimized vitamin K2 helps to treat osteoporosis

Osteoporosis is a common debilitating bone disease, which is characterized by bone loss and degeneration of bone structure, primarily caused by an imbalance between bone formation by osteoblasts and bone resorption by osteoclasts. ...

Medical research

Making bones is less difficult than was previously thought

The way in which bone formation occurs needs to be redefined. This was revealed by Radboud university medical center researchers and their colleagues in a publication in Nature Communications. It turns out that bone formation ...

Medical research

Smart bones curve to protect against fracture

Bones grow curved in response to pressure and strain and these changes can be long-lasting, according to a new study by UCL, the Royal Veterinary College London and the Max Planck Institute.

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Ossification

Ossification is a medical term that is synonymous with bone tissue formation. Endochondral ossification and intramembranous ossification are two processes resulting in the formation of normal, healthy bone tissue. Heterotopic ossification is a process resulting in the formation of bone tissue, that is often atypical, at an extraskeletal location. Calcification is a medical term that is often confused with ossification. Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue. Calcification is a process that occurs during ossification, but not vice versa.

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