Medical research

Smart bones curve to protect against fracture

Bones grow curved in response to pressure and strain and these changes can be long-lasting, according to a new study by UCL, the Royal Veterinary College London and the Max Planck Institute.

HIV & AIDS

Drinking weakens bones of people living with HIV: study

For people living with HIV, any level of alcohol consumption is associated with lower levels of a protein involved in bone formation, raising the risk of osteoporosis, according to a new study by researchers from the Boston ...

Diseases, Conditions, Syndromes

New osteoporosis therapy's dual effects on bone tissue

Sclerostin is a protein produced by osteocytes in the bone that inhibits bone formation. A recent analysis of results from a clinical trial reveals the beneficial effects of romosozumab, an antibody therapy that targets sclerostin, ...

Medical research

Stem cell signal drives new bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to ...

Immunology

Probiotics increase bone volume in healthy mice

A widely-used probiotic stimulates bone formation in young female mice, according to a study published November 13th in the journal Immunity. In response to treatment with Lactobacillus rhamnosus GG (LGG), other intestinal ...

Diseases, Conditions, Syndromes

New mechanism activates bone-building cells in osteoperosis

The number of osteoporosis medications that promote bone formation are few compared to those that suppress bone resorption. A research group led by Kumamoto University scientists has discovered that the gene SIRT7 is important ...

Medical research

The art of building bone

Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicates the emerging role of chondrocyte-to-osteoblast ...

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Ossification

Ossification is a medical term that is synonymous with bone tissue formation. Endochondral ossification and intramembranous ossification are two processes resulting in the formation of normal, healthy bone tissue. Heterotopic ossification is a process resulting in the formation of bone tissue, that is often atypical, at an extraskeletal location. Calcification is a medical term that is often confused with ossification. Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue. Calcification is a process that occurs during ossification, but not vice versa.

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