Inflammatory disorders

Cellular changes lead to chronic allergic inflammation in the sinus

Chronic rhinosinusitis is distinct from your average case of seasonal allergies. It causes the sinuses to become inflamed and swollen for months to years at a time, leading to difficulty breathing and other symptoms that ...

Immunology

Novel insights on 'leaky' gut

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the small and the large intestine. IBD patients experience bloody diarrhea and abdominal pain and have an increased risk of developing colon cancer.

Immunology

How good bacteria can help keep a gut healthy

New research reveals a cellular mechanism by which good bacteria can help the gut stay healthy. The study, which appears in the journal Immunity, shows that good bacteria, or the microbiota, interact with both the epithelial ...

Immunology

Chemotherapy-induced diarrhea traced to immune cells

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smooth muscle lining the ...

Oncology & Cancer

Antifungal drug eliminates sleeping bowel cancer cells in mice

An antifungal medication, commonly prescribed for toenail infections, could help eliminate dormant cells within bowel tumours, according to new research funded by Cancer Research UK and published in the Journal of Experimental ...

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