Immunology

How to engineer a stronger immune system

With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease ...

Immunology

Long noncoding RNA found to quell inflammation

A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School. Abundantly found in macrophages, ...

Immunology

Regulation of semiochemicals in inflammation

Tumour necrosis factor-alpha (TNF-α) is a central signalling substance of the immune system and involved in many inflammatory processes. Blocking this molecule is the foundation of modern treatment against inflammatory diseases ...

Diseases, Conditions, Syndromes

Study advances understanding of colon cancer and colitis

Inflammatory bowel disease (IBD), of which Crohn's disease and ulcerative colitis are the main types, is on the increase in the United States, affecting more than 1.6 million people and explaining perhaps the increase in ...

Diseases, Conditions, Syndromes

Study shows ozanimod as effective in treating ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical ...

Medical research

Controlling cell turnover in the intestinal lining

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. ...

Immunology

Immune cells' bacteria may fight chronic inflammation

A population of bacteria inhabits human and mouse immune cells and appears to protect the body from inflammation and illness, Weill Cornell Medicine scientists discovered in a new study. The findings challenge conventional ...

Health

Green tea and iron, bad combination

Green tea is touted for its many health benefits as a powerful antioxidant, but experiments in a laboratory mouse model of inflammatory bowel disease suggest that consuming green tea along with dietary iron may actually lessen ...

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