Immunology

Colon signaling pathway key to inflammatory bowel disease

The intestine encounters more foreign substances and potential toxins than other parts of the body, so it is not surprising that a healthy gut is maintained by the tight control of immune responses. These protect against ...

Immunology

Scientists discover promising off-switch for inflammation

Scientists have discovered a new metabolic process in the body that can switch off inflammation. They have discovered that 'itaconate'—a molecule derived from glucose—acts as a powerful off-switch for macrophages, which ...

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