One of the most puzzling—and devastating—aspects of cancer is its potentially lethal wanderlust, the spread of the disease from a primary tumor to a new and distant site.
Breast cancer is the second most common cause of brain metastasis, which occurs in 10% to 30% of patients with metastatic breast cancer. Breast cancer patients who develop brain metastasis have limited treatment options and ...
Dec 14, 2023
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Nearly half of all patients with brain metastasis experience cognitive impairment. Until now, it was thought that this was due to the physical presence of the tumor pressing on neural tissue. But this "mass effect" hypothesis ...
Aug 30, 2023
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When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that ...
Jun 20, 2023
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In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain.
Aug 31, 2022
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Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics ...
Mar 8, 2021
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Approximately 15-to-30 percent of patients with metastatic breast cancer have brain metastasis (BM), with basal-like breast cancer (BLBC) metastasizing to the brain most frequently. The prognosis for BLBC-BM patients is poor, ...
Mar 5, 2021
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Lung cancer spreads to the brain in about one-quarter of patients with an advanced form of the disease. To date, radiation has been the only treatment option, but it comes with toxic side effects. Researchers at Yale Cancer ...
Apr 14, 2020
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A study published in Nature Medicine by a team led by Manuel Valiente, head of the Brain Metastasis Group at the Spanish National Cancer Research Centre (CNIO), shows that the administration of silibinin in patients with ...
Jun 11, 2018
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Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response ...
Aug 4, 2017
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