Alzheimer's disease & dementia

New insight into role of amyloid beta in Alzheimer's disease

New Alzheimer's disease research details a technique that speedily measures levels in the brain of a damaging protein fragment, and insight into why mutations in a specific gene increase the risk of developing the disease.

Alzheimer's disease & dementia

Immune cells may protect against Alzheimer's

Clusters of immune cells in the brain previously associated with Alzheimer's actually protect against the disease by containing the spread of damaging amyloid plaques, a new Yale University School of Medicine study shows.

Alzheimer's disease & dementia

Investigating plasma levels as a biomarker for Alzheimer's disease

A Centre for Healthy Brain Ageing (CHeBA) paper published in Current Alzheimer Research presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain ...

Alzheimer's disease & dementia

Study reveals the possibility of curbing synapse loss in Alzheimer's

Researchers at Boston Children's Hospital show how brain connections, or synapses, are lost early in Alzheimer's disease and demonstrate that the process starts—and could potentially be halted—before telltale plaques ...

Alzheimer's disease & dementia

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in the March 30 issue of Science ...

Alzheimer's disease & dementia

Inflammatory changes in the brain twenty years before Alzheimer onset

Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, according to a new study from Karolinska Institutet published in the medical scientific journal ...

Alzheimer's disease & dementia

Alzheimer-type brain pathology after transplantation of dura mater

Up to now Alzheimer's disease has not been recognized as transmissible. Now researchers at the University of Zurich and the Medical University Vienna demonstrated Alzheimer-type pathology in brains of recipients of dura mater ...

Alzheimer's disease & dementia

Geometric study of brain cells could change strategies on Alzheimer's

Applying mathematical models used for studying the galaxies or interactions between elementary particles, researchers at the Institute of Neuroscience of the Universitat Autònoma de Barcelona, in collaboration with Massachusetts ...

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