Oncology & Cancer

Faulty DNA repair may lead to BRCA-linked cancers

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators. The discovery has potential ...

Oncology & Cancer

New study illuminates why cancers caused by BRCA mutations recur

Researchers at the University of Pennsylvania's Basser Center for BRCA at the Abramson Cancer Center have discovered factors that may make breast and ovarian cancers associated with BRCA1/2 gene mutations more likely to recur.

Oncology & Cancer

Variants in BRCA1/2 and MMR genes in children with cancer

Pathogenic variants in BRCA1/2 genes are associated with an increased risk of breast and ovarian cancer in adults, and variants in mismatch repair (MMR) genes increase the risk of gastrointestinal and other cancers. Until ...

page 4 from 23