In a recent study published in JAMA Oncology, investigators from the University of Bergen, in collaboration with the Women's Health Initiative (WHI) study in the U.S., reported epigenetic gene silencing in normal tissue to ...
Sep 20, 2022
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Just as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to chemotherapy. And among tumors, those associated with triple negative breast cancer and ovarian ...
Pathogenic variants in BRCA1/2 genes are associated with an increased risk of breast and ovarian cancer in adults, and variants in mismatch repair (MMR) genes increase the risk of gastrointestinal and other cancers. Until ...
Aug 24, 2022
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Telling a child about their mother's risk of hereditary breast and ovarian cancer does not adversely influence the offspring's lifestyle or quality of life in the long term, according to a new study led by researchers at ...
Jul 21, 2022
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Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer—but not every mutation in the gene is harmful. To better equip patients and their doctors to understand and manage ...
Jun 3, 2022
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Too many women are getting unnecessary mastectomies and other invasive procedures because of a knowledge gap about differences in cancer genes. A new study offers a path to closing the gap.
May 3, 2022
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Results of a biomarker analysis of the NRG Oncology NRG-GY004 trial were presented at a Seminal Session during the Society for Gynecologic Oncology's (SGO) Annual Meeting on Women's Cancer in March 2022. The analysis, which ...
Mar 21, 2022
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The results from the major phase III OlympiA trial shows the drug improves survival rates in women who have inherited faults in their BRCA1 or BRCA2 genes.
Mar 17, 2022
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Scientists may better understand and test for the genetic variations that cause cancer and other heritable diseases through the application of a novel strategy for securely sharing and analyzing genomic data developed at ...
Mar 9, 2022
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Researchers at the University of Toronto's Leslie Dan Faculty of Pharmacy have uncovered mechanisms that help to explain how the breast cancer 1 susceptibility protein (BRCA1), best known for its role in suppression of breast ...
Jan 28, 2022
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