Oncology & Cancer
New insight into aggressive breast cancers
Scientists from Cardiff University have uncovered a protein which drives aggressive breast cancer and could be targeted for developing new and improved therapies.
Dec 27, 2018
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News tagged with brca1 gene
Oncology & Cancer
Insights into breast cancer gene that could lead to better risk screening
Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer—but not every mutation in the gene is harmful. To better equip patients and their doctors to understand and manage ...
Jun 3, 2022
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Oncology & Cancer
Olaparib shows promise in treating ovarian cancer, even without BRCA mutations
The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...
Aug 21, 2011
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Oncology & Cancer
Blocking DNA production in cancer therapy by targeting the POLtheta enzyme
BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop. ...
Nov 17, 2022
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Oncology & Cancer
African-American and white women share genes that increase breast cancer risk
The same genes that greatly increase the risk of breast cancer in U.S. white women, including women of Ashkenazi Jewish descent, also greatly increase breast cancer risk among African American women. These genes include the ...
May 19, 2020
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Oncology & Cancer
Faulty gene connected to ovarian cancer risk
In a new study published in Nature Genetics researchers say that women who possess a fault in a gene named RAD51D have a greater risk of developing ovarian cancer than women who do not have this fault and tests are expected ...
Genetics
Breast cancer gene protects against obesity, diabetes
(Medical Xpress)—The gene known to be associated with breast cancer susceptibility, BRCA 1, plays a critical role in the normal metabolic function of skeletal muscle, according to a new study led by University of Maryland ...
Mar 12, 2014
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Oncology & Cancer
Research shows breast cancer gene affects brain development
(Medical Xpress)—The BRCA1 gene, known for its role in suppressing the growth of breast and ovarian tumors, could be necessary for brain development. In a study appearing in the Proceedings of the National Academy of Sciences, ...
Oncology & Cancer
BRCA1 mutations in breast and ovarian cancer can predict treatment resistance
Mutations in the BRCA1 gene are one of the most common risk factors for breast and ovarian cancers. Although tumors that harbor BRCA1 mutations initially respond well to cancer treatments, many tumors eventually become less ...
Jul 25, 2016
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Oncology & Cancer
Hundreds more breast cancer patients should be tested for BRCA1 gene
(Medical Xpress) -- Leading breast cancer experts are calling for women under 50 who are diagnosed with triple-negative (TN) breast cancer to be offered testing for faults in the BRCA1 gene, according to a report published ...
Feb 15, 2012
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