Oncology & Cancer
Simpler name for cancer genetic syndrome could save lives
As medical science links certain genetic mutations with a greater variety of cancers, the names for these risk syndromes are falling out of step.
Jul 4, 2019
0
1
News tagged with brca2 mutations
Genetics
Mystery of breast cancer risk gene solved, 20 years after its discovery
More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc.
Oct 4, 2017
0
26
Oncology & Cancer
Searching for the 'signature' causes of BRCAness in breast cancer
Breast cancer cells with defects in the DNA damage repair-genes BRCA1 and BRCA2 have a mutational signature (a pattern of base swaps—e.g., Ts for Gs, Cs for As—throughout a genome) known in cancer genomics as "Signature ...
Aug 21, 2017
0
2
Oncology & Cancer
Gene increases risk of breast cancer to one in three by age 70
Breast cancer risks for one of potentially the most important genes associated with breast cancer after the BRCA1/2 genes are today reported in the New England Journal of Medicine. Women with mutations in the PALB2 gene have ...
Aug 6, 2014
0
0
Oncology & Cancer
Study links another gene variant to male breast cancer
(HealthDay)—Researchers report that they've identified another genetic variation that appears connected to male breast cancer, a rare condition that kills several hundred men in the United States each year.
Sep 23, 2012
0
0
Oncology & Cancer
Diagnostic chest radiation before 30 may increase breast cancer risk
Women carrying a mutation in the BRCA1- or BRCA2- genes (which control the suppression of breast and ovarian cancer) who have undergone diagnostic radiation to the chest before the age of 30 are more likely to develop breast ...
Sep 6, 2012
0
0
Oncology & Cancer
Study finds first major genetic mutation associated with hereditary prostate cancer risk
After a 20-year quest to find a genetic driver for prostate cancer that strikes men at younger ages and runs in families, researchers have identified a rare, inherited mutation linked to a significantly higher risk of the ...
Jan 11, 2012
0
0
Oncology & Cancer
Faulty BRCA genes linked to prostate and pancreatic cancers
Faulty versions of the BRCA1 and BRCA2 genes are well known to increase the risk of breast cancer in men and women, and in ovarian cancer. Now BRCA1 and BRCA2 have been linked to several other cancers, including those that ...
Jan 25, 2022
0
43
Oncology & Cancer
Rapid genetic testing can help women choose breast cancer treatment
Women with breast cancer who are offered rapid genetic testing for BRCA1 and BRCA2 mutations—and who are able to receive their genetic test results prior to selecting treatment—were more likely to choose to have a bilateral ...
Mar 31, 2021
0
16
Oncology & Cancer
Immune system could be trained to spot drug-resistant cancers
Aggressive cancers could be treated with immunotherapies that direct the immune system to kill cancer cells with specific drug resistance-causing mutations, a major new study suggests.
Jul 23, 2020
0
20
