Oncology & Cancer

Study sheds light on regulation of breast cancer initiation

Tumor cells are characterized by high degree of heterogeneity and among them, tumor-initiating cells (TICs), sometimes also called cancer stem-like cells, are considered as the culprits of cancer development and progression, ...

Oncology & Cancer

Cancer cells alter protein production machinery to hasten metastasis

Hormone receptor-positive breast cancer can spread throughout the body via the bloodstream as circulating tumor cells, or CTCs, which eventually reach distal (remote) body sites to form metastatic tumors. An increase in ribosomes, ...

Oncology & Cancer

Researchers discover key protein in endometrial cancer growth

The hormone estrogen plays many critical roles in men and women, in both healthy tissues and in cancer. In breast and gynecologic cancers, estrogen sends signals to tumors instructing the cancer cells to grow out of control. ...

Oncology & Cancer

New therapy option identified for early-stage breast cancer

Radionuclide therapy has proven successful in delaying the growth of disseminated tumor cells (DTCs) in early-stage breast cancer in a small animal model, suggesting its use as a potential adjuvant therapy for retarding the ...

Oncology & Cancer

Protein AKAP8 suppresses breast cancer metastasis

A protein naturally produced in the body has been found to suppress breast cancer metastasis in animal models of human tumors. Researchers led by Baylor College of Medicine also found that high levels of this protein, AKAP8, ...

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