Oncology & Cancer

PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer

Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...

Oncology & Cancer

Chemo-Linked factors may impact weight in breast cancer

(HealthDay) -- Adjuvant chemotherapy for early-stage breast cancer can induce weight gain and a variety of metabolic changes that may be associated with a poor prognosis for some patients, according to research published ...

Oncology & Cancer

New point of attack for breast cancer with poor prognosis

(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research describe how the protein phosphatase SHP2 promotes breast cancer with poor prognosis. As they report in the latest issue of Nature ...

Oncology & Cancer

A two-pronged attack: Why loss of STAT1 is bad news

Breast cancer represents about a fifth of all cancers diagnosed in women. The reasons for the rapid progression of the disease remain relatively poorly understood but recent work in the group of Veronika Sexl at the University ...

Oncology & Cancer

Enhancing the effectiveness of a breast cancer treatment

Breast cancers expressing the protein HER2 have a particularly poor prognosis. Treatment with trastuzumab (Herceptin) benefits some patients with HER2-positive breast cancer, but it is not as effective as had been hoped. ...

Oncology & Cancer

Researchers train computer to evaluate breast cancer

Since 1928, the way breast cancer characteristics are evaluated and categorized has remained largely unchanged. It is done by hand, under a microscope. Pathologists examine the tumors visually and score them according to ...

Oncology & Cancer

Cellular origin of a rare form of breast cancer identified

Identifying the cellular origins of breast cancer might lead to earlier diagnosis and more efficient management of the disease. New research led by Charlotte Kuperwasser of Tufts University School of Medicine (TUSM) has determined ...

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