Medical research

Crucial step in cell division discovered

(Medical Xpress) -- Cancer Research UK scientists have discovered how cells ‘pinch in’ at the middle in order to split into two new cells. Their research is published in Developmental Cell today.

Medical research

Study finds direct oxidative stress damage shortens telomeres

The same sources thought to inflict oxidative stress on cells—pollution, diesel exhaust, smoking and obesity—also are associated with shorter telomeres, the protective tips on the ends of the chromosomal shoelace.

Oncology & Cancer

Cancer cell's 'self eating' tactic may be its weakness

Cancer cells use a bizarre strategy to reproduce in a tumor's low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising ...

Oncology & Cancer

First-in-class targeted microRNA therapy slows cancer tumor growth

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division. As reported in Oncogene, tumors treated with the ...

Oncology & Cancer

'Pulverized' chromosomes linked to cancer?

They are the Robinson Crusoes of the intracellular world -- lone chromosomes, whole and hardy, stranded outside the nucleus where their fellow chromosomes reside. Such castaways, each confined to its own "micronucleus," are ...

Medical research

Blocking two enzymes could make cancer cells mortal

EPFL scientists have identified two enzymes that protect chromosomes from oxidative damage and shortening. Blocking them might be a new anticancer strategy for stopping telomerase, the enzyme that immortalizes tumors.

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