Oncology & Cancer

Early promise for first targeted brain cancer treatment

A new drug could become the first ever targeted brain cancer treatment, with encouraging early results from a phase 1 trial suggesting it could treat some patients with advanced disease.

Medical research

Targeted therapy for 'undruggable' lung cancer

Over the past two decades, targeted cancer therapies have changed the prognosis for thousands of patients. By targeting the specific genetic mutation behind a patient's cancer, these therapies have enabled increasing numbers ...

Oncology & Cancer

Predicting resistance to anticancer drugs

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may ...

Oncology & Cancer

Toward the first drug to treat a rare, lethal liver cancer

Treatment options for a deadly liver cancer, fibrolamellar carcinoma, are severely lacking. Drugs that work on other liver cancers are not effective, and although progress has been made in identifying the specific genes involved ...

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