Treatment resistance caused by cancer cell plasticity constitutes a major challenge in the treatment of prostate cancer. A recent study from the University of Eastern Finland Institute of Biomedicine published in Nucleic ...
Jun 3, 2024
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A new proof-of-concept study by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) shows that changing only a single letter in the DNA code of selected genes in T cells may lead to improved cell therapy. ...
May 29, 2024
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Novel therapeutic approaches are needed for children with diffuse midline glioma (DMG) and other recurrent high-grade central nervous system (CNS) tumors, aggressive brain cancers with poor prognoses. A type of immunotherapy ...
May 22, 2024
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When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. ...
May 16, 2024
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Harnessing the body's own cells to fight disease, long a medical dream, is finally a reality.
May 13, 2024
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CAR T cell therapy has proven effective in treating various hematological cancers. However, not all patients respond equally well to treatment. In a clinical study, researchers from the University of Leipzig Medical Center ...
Apr 26, 2024
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Breast cancer is the second-most common cancer diagnosis for U.S. women, and the second-leading cause of female cancer deaths. In recent years, breast cancer treatments have improved significantly, thanks to targeted gene ...
Apr 24, 2024
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New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...
Apr 16, 2024
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Scientists have discovered how breast cancer cells can "hibernate" to avoid treatment and "wake up" years later—causing a relapse that is more difficult to treat.
Mar 26, 2024
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Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell ...
Mar 21, 2024
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