A research paper titled "A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis" was recently published in Oncotarget.
Jun 8, 2022
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As an approach to personalized medicine, a new Nature Communications study proposes that "mutational footprints" of DNA repair are a promising predictive genetic marker for determining which tumors will respond to certain ...
May 26, 2022
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Radiation therapy is a proven approach to destroying tumors. However, it is possible that it might be able to do even more in the future—namely stimulate the immune system at the same time and so fight cancer even more ...
Apr 20, 2022
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A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and ...
Apr 19, 2022
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Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results ...
Apr 12, 2022
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Researchers at The University of Texas MD Anderson Cancer Center have developed a new bioinformatics platform that predicts optimal treatment combinations for a given group of patients based on co-occurring tumor alterations. ...
Apr 12, 2022
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A new study from researchers at the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist Hospital shows that cancer patients who receive treatment with genetically ...
Mar 30, 2022
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The first FDA-approved gene therapies are living drugs: immune cells taken from cancer patients engineered to target tumor cells. However, for many patients, these advanced therapies do not result in a long-lasting remission. ...
Mar 16, 2022
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While gene mutations can lead to drug resistance, researchers in the Perelman School of Medicine at the University of Pennsylvania have identified an important, non-genetic adaptation that could also drive resistance to targeted ...
Mar 1, 2022
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Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored ...
Feb 15, 2022
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