To treat the liver disorder tyrosinaemia type I, one of the most severe forms of the disease, doctors typically use drug therapy. However the treatment is lifelong and a residual risk of liver cancer persists, which is usually ...
Aug 31, 2016
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New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma. A McGill-led study published in Nature Communications reveals that suppressing ...
Aug 17, 2020
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A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and ...
Apr 19, 2022
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Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when ...
Jun 30, 2011
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(Medical Xpress) -- Mutations to a gene called p53 have been linked to half of all cancers, leading to tumor growth and the spread of cancerous cells. Now, a Cornell-led study identifies for the first time the mechanisms ...
Aug 24, 2011
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Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant ...
Jan 24, 2023
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The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of ...
Jan 12, 2018
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Researchers at UC Santa Cruz have demonstrated a new, rapid method to obtain donor stem cells for bone marrow transplants using a combination of Viagra and a second drug called Plerixafor.
Oct 10, 2019
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The first FDA-approved gene therapies are living drugs: immune cells taken from cancer patients engineered to target tumor cells. However, for many patients, these advanced therapies do not result in a long-lasting remission. ...
Mar 16, 2022
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By reprogramming tumor cells to become the body's defenders, Filipe Pereira and his colleagues hope to improve current cancer treatments.
Dec 22, 2022
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