Oncology & Cancer

How genetics play a role in developing melanoma

A recent study from Cleveland Clinic shows that melanoma, which is the most serious type of skin cancer, isn't just caused by environmental factors. Researchers discovered genetics can also play a role.

Oncology & Cancer

Variants in BRCA1/2 and MMR genes in children with cancer

Pathogenic variants in BRCA1/2 genes are associated with an increased risk of breast and ovarian cancer in adults, and variants in mismatch repair (MMR) genes increase the risk of gastrointestinal and other cancers. Until ...

Medications

Tabrecta gains full FDA approval for non-small cell lung cancer

The U.S. Food and Drug Administration granted regular approval to capmatinib (Tabrecta) for adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have a genetic mutation leading to mesenchymal-epithelial ...

Oncology & Cancer

Genetic mapping of tumors reveals how cancers grow

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically over time. This has been made possible using a new ...

Medical research

Collagen a key player in breast cancer metastasis

Collagen type XII plays a key role in regulating the organization of the tumor matrix, reveals a new study from the Garvan Institute of Medical Research. A team of scientists led by Associate Professor Thomas Cox, Head of ...

Oncology & Cancer

How common genetic alterations cause kidney cancer

An international group of researchers investigated why mutations often associated with renal cancer result specifically in renal cancer, instead of other cancer types.

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