An analysis of 13,000 tumors highlights two previously overlooked genes as potential new therapeutic targets for cancer treatment. The researchers have also identified potential new therapeutic targets for male infertility. ...
May 7, 2020
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Most breast cancers utilize the female hormone estrogen to grow, so drug-induced estrogen deprivation is used as a treatment in many patients. However, cancer will recur in one-third of these patients. A research team at ...
Apr 22, 2020
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Fatty liver disease not associated with alcohol consumption, which is called Nonalcoholic Fatty Liver Disease or NAFLD, affects more than one billion people worldwide. Even in children the numbers are overwhelming, with up ...
Apr 7, 2020
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Medical experts have always known myelin, the protective coating of nerve cells, to be metabolically inert. A study led by The University of Texas MD Anderson Cancer Center has found that myelin is surprisingly dynamic, a ...
Mar 23, 2020
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Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize ...
Feb 24, 2020
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Serine racemase (SRR) is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate. Though already well characterized, a team of researchers led ...
Jan 29, 2020
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The size of the human brain increased profoundly during evolution. A certain gene that is only found in humans triggers brain stem cells to form a larger pool of stem cells. As a consequence, more neurons can arise, which ...
Jan 7, 2020
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Recent evidence suggests a link between cholesterol metabolism and innate immunity. Upon viral infection, macrophages show reduced cholesterol synthesis accompanied by enhanced expression of antiviral genes, including type ...
Dec 27, 2019
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Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often ...
Dec 12, 2019
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Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments. The enzyme that controls the ...
Nov 26, 2019
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