A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell—nucleotide metabolism—to help identify new drugs that specifically ...
Nov 18, 2019
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A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.
Nov 8, 2019
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On the morning of Oct. 7, I woke up with the message from a colleague saying that "HIF got the 2019 Nobel Prize in Physiology or Medicine whoo hooo." That's exciting news for young researchers like me who are beginning our ...
Oct 9, 2019
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Researchers at The University of Texas at Austin and Baylor College of Medicine have developed a new preoperative test for thyroid cancer that is faster and about two-thirds more accurate than the diagnostic tests doctors ...
Oct 7, 2019
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A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber ...
Sep 25, 2019
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that ...
Sep 25, 2019
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Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat ...
Sep 12, 2019
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Cancer researchers are setting their sights on a new kind of cancer treatment that targets the tumor's surrounding environment, called the tumor microenvironment, in contrast to targeting the tumor directly.
Sep 4, 2019
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Cancer cells can adapt and develop resistance to chemotherapy drugs, making it difficult to eradicate tumors. A new study led by investigators from Brigham and Women's Hospital suggests that a combination of three drugs, ...
Aug 20, 2019
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The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune ...
Aug 19, 2019
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