Oncology & Cancer

Possible key to beating colorectal cancer

Serine racemase (SRR) is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate. Though already well characterized, a team of researchers led ...

Neuroscience

Cancer-like metabolism makes brain grow

The size of the human brain increased profoundly during evolution. A certain gene that is only found in humans triggers brain stem cells to form a larger pool of stem cells. As a consequence, more neurons can arise, which ...

Medical research

Metabolic adaptation ensures survival of colon cancer cells

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often ...

Oncology & Cancer

New screening method identifies inhibitors of cancer cell metabolism

A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell—nucleotide metabolism—to help identify new drugs that specifically ...

Medical research

Discovery of how cells sense oxygen levels earns Nobel Prize

On the morning of Oct. 7, I woke up with the message from a colleague saying that "HIF got the 2019 Nobel Prize in Physiology or Medicine whoo hooo." That's exciting news for young researchers like me who are beginning our ...

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