Oncology & Cancer

How cancer cells rewire their metabolism to survive

Cancer cells need food to survive and grow. They're very good at getting it, too, even when nutrients are scarce. Many scientists have tried killing cancer cells by taking away their favorite food, a sugar called glucose. ...

Oncology & Cancer

Diabetes drug could hold promise for lung cancer patients

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work ...

Genetics

A scanner for hereditary defects

Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. Researchers from ...

Oncology & Cancer

Physical activity cuts mortality in colorectal cancer survivors

(HealthDay)—For patients with invasive, non-metastatic colorectal cancer, increased recreational physical activity is associated with reduced all-cause mortality, while prolonged sedentary time correlates with increased ...

Oncology & Cancer

Study of cancer cell metabolism yields new insights on leukemia

University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have ...

Oncology & Cancer

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Oncology & Cancer

Cellular fuel gauge may hold the key to restricting cancer growth

Researchers at McGill University have discovered that a key regulator of energy metabolism in cancer cells known as the AMP-activated protein kinase (AMPK) may play a crucial role in restricting cancer cell growth. AMPK acts ...

Health

Toasting your health: Take care with alcohol consumption

(Medical Xpress)—The holidays are a time to consume—food, gifts, and spirits. Here are a few alcohol-related story ideas from The Methodist Hospital. Because alcohol's effects on human physiology are complex, advice about ...

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