Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths. There is a clear need to better understand the processes that enable ...
Feb 1, 2023
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In the process of metastasis, the movement of cancer cells to different parts of the body, a specific master regulator gene plays a central role: a transcription factor named Sox4 activates a sequence of genes and triggers ...
Jun 10, 2013
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At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA.
Jun 2, 2016
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Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have made a landmark discovery in the battle against the rapid spread of aggressive cancers associated with PRL-3 oncoprotein . Contrary to the current ...
Sep 8, 2011
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Future treatments for advanced cancer could work by sticking cancer cells in place and preventing their spread around the body. A new study by researchers at the University of California, Davis, and the University of Washington ...
Aug 3, 2022
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In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential "silver bullet" for preventing and treating it. The findings may extend to ...
Jul 26, 2017
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Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called ...
May 29, 2012
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Tumors that produce more stress granules are more likely to metastasize, according to a study published in The Journal of Cell Biology. The results suggest that drugs to inhibit the formation of these structures might rein ...
Mar 23, 2015
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Most cancer deaths occur because of metastasis, yet progress in preventing and treating migratory cancer cells has been slow.
Nov 6, 2014
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Researchers at Tel Aviv University developed a new therapeutic strategy based on existing medications to inhibit bone metastasis in breast cancer patients. Using both an animal model and tissue samples from patients in Israel ...
Apr 2, 2024
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