Oncology & Cancer

VCP/p97 as a therapeutic target in KRAS-mutant pancreatic cancer

A new research paper, titled "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer," was published in Genes & Cancer on March ...

Diseases, Conditions, Syndromes

The world's first mRNA vaccine for deadly bacteria

For the first time in the world: a team of researchers from Tel Aviv University and the Israel Institute for Biological Research have developed an mRNA-based vaccine that is 100% effective against a type of bacteria that ...

Medical research

How oxygen deprivation causes cancer cells to spread

In breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. Ph.D. candidate Qiuyu ...

Oncology & Cancer

New gene implicated in cancer, cellular stress response

Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity, according to findings published in Nature Communications.

Medications

Researchers use a new approach to hit an 'undruggable' target

The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category. Now, University of Michigan Rogel Cancer Center researchers have found success ...

Medical research

Study suggests possible way to 'Smac' cancer

In animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by inhibitor of apoptosis proteins (IAPs), guards against excessive cell death. Together these ...

page 17 from 40