A recent study that shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combatting drug resistance when treating microbial infections or cancer. Led by Gábor ...
Apr 15, 2022
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For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...
Apr 12, 2022
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Researchers from The University of Texas MD Anderson Cancer Center showed that natural killer (NK) cells derived from donated umbilical cord blood, combined with a novel bispecific antibody known as AFM13 that targets CD16A ...
Apr 10, 2022
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Liver cancer is one of the most serious cancers in China. Tumor-initiating cells (TICs), a small subset of cells in the tumor bulk with self-renewal and differentiation capacities, play key roles in tumor formation, metastasis, ...
Apr 8, 2022
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A research team led by Prof. Liu Qingsong and Liu Jing from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has recently found that nintedanib, a multikinase inhibitor of the receptor ...
Apr 7, 2022
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A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer. The assay could be used to identify new drugs to treat ...
Apr 6, 2022
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While gene mutations can lead to drug resistance, researchers in the Perelman School of Medicine at the University of Pennsylvania have identified an important, non-genetic adaptation that could also drive resistance to targeted ...
Mar 1, 2022
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The effect of iron supplementation on skeletal muscle atrophy in cancer patients and sufferers from other wasting diseases has been investigated by a team of Italian and Belgian scientists which studied causes of these conditions ...
Feb 25, 2022
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Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the ...
Feb 24, 2022
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Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs ...
Feb 18, 2022
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