Oncology & Cancer

Deadly lung cancers are driven by multiple genetic changes

A new UC San Francisco-led study challenges the dogma in oncology that most cancers are caused by one dominant "driver" mutation that can be treated in isolation with a single targeted drug. Instead, the new research finds ...

Oncology & Cancer

Why do perfectly good cancer treatments suddenly stop working?

Kris Wood, PhD, had been going full tilt for more than six months, ever since he'd been hired to the faculty in the Department of Pharmacology and Cancer Biology at Duke. He was working 12 stressful hours a day, adjusting ...

Oncology & Cancer

Researchers find novel mechanism of resistance to anti-cancer drugs

The targeted anti-cancer therapies cetuximab and panitumumab are mainstays of treatment for advanced colorectal cancer, the second leading cause of cancer-related deaths in the United States. However, many patients have tumors ...

Oncology & Cancer

Genetic targets to chemo-resistant breast cancer identified

Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.

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