Oncology & Cancer

Cell therapy could improve bone marrow transplant safety

UCLA researchers report a step forward in the development of an "off-the-shelf" cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment ...

Oncology & Cancer

Protein transformation drives cancer development

A change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of more aggressive cancerous cells, according to a recent Northwestern Medicine study published ...

Oncology & Cancer

Mental illness elevated among Hodgkin lymphoma patients

Patients with Hodgkin lymphoma (HL) are more likely to suffer from mental-health and substance-abuse disorders than the general population. Calling for more attention to mental health, a study published August 2 in Cancer ...

Oncology & Cancer

New injectable gel offers promise for tough-to-treat brain tumors

Like the hardiest weed, glioblastoma almost always springs back—usually within months after a patient's initial brain tumor is surgically removed. That is why survival rates for this cancer are just 25 percent at one year ...

Medical research

Inflammation accelerates aging of the hematopoietic system

In mice, inflammation in early to mid-life leads to a permanent decline in functional blood stem cells, according to a recent publication by scientists from the German Cancer Research Center (DKFZ) and the Stem Cell Institute ...

Oncology & Cancer

Making better, ready-made CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells from a patient's own blood are engineered to carry so-called chimeric antigen receptors (CAR) that enhance the T cells' ability to attack and kill tumor cells. While CAR-T therapy is a ...

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