Oncology & Cancer

Cell therapy could improve bone marrow transplant safety

UCLA researchers report a step forward in the development of an "off-the-shelf" cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment ...

Oncology & Cancer

Protein transformation drives cancer development

A change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of more aggressive cancerous cells, according to a recent Northwestern Medicine study published ...

Oncology & Cancer

Mental illness elevated among Hodgkin lymphoma patients

Patients with Hodgkin lymphoma (HL) are more likely to suffer from mental-health and substance-abuse disorders than the general population. Calling for more attention to mental health, a study published August 2 in Cancer ...

Oncology & Cancer

New injectable gel offers promise for tough-to-treat brain tumors

Like the hardiest weed, glioblastoma almost always springs back—usually within months after a patient's initial brain tumor is surgically removed. That is why survival rates for this cancer are just 25 percent at one year ...

Oncology & Cancer

Making better, ready-made CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells from a patient's own blood are engineered to carry so-called chimeric antigen receptors (CAR) that enhance the T cells' ability to attack and kill tumor cells. While CAR-T therapy is a ...

Medical research

Inflammation accelerates aging of the hematopoietic system

In mice, inflammation in early to mid-life leads to a permanent decline in functional blood stem cells, according to a recent publication by scientists from the German Cancer Research Center (DKFZ) and the Stem Cell Institute ...

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