Medical research

Study reveals factors behind embryonic stem cell state

Embryonic stem cells (ESC) have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body. The embryonic stem cell state is established and maintained by multiple regulatory ...

Oncology & Cancer

Two genes slow down the development of intestinal tumors

Benign intestinal tumors with mutations that delete or inactivate two particular tumor-suppressing genes develop more quickly towards cancerous forms, according to new research from the Crick.

Medical research

Stem-cell niche for 10 billion colon cells a day

Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible ...

Genetics

Gene therapy using lentivirus promising in three youngsters

Two Houston researchers from Baylor College of Medicine and Texas Children's Hospital were part of an international team that developed a new gene therapy approach to treatment of Wiskott-Aldrich Syndrome, a fatal inherited ...

Oncology & Cancer

CAR-T immunotherapies may have a new player

Emerging CAR-T immunotherapies leverage modified versions of patient's T-cells to target and kill cancer cells. In a new study, published June 28 online in Cell Stem Cell, researchers at University of California San Diego ...

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