Oncology & Cancer

Researchers uncover how colorectal cancer cells colonize the liver

In cases where cancer is fatal, 9 out of 10 times the culprit is metastasis. This is when the primary tumor has sent out cells, like seeds, and invaded other organs of the body. While medicine has made great progress in treating ...

Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

Oncology & Cancer

Researchers learn how cancer cells divide despite treatment

Researchers in the lab of Jean Cook, Ph.D., chair and professor in the Department of Biochemistry and Biophysics, have identified the cellular processes that occur when you take a cancer drug meant to stop rapid cell growth ...

Medical research

Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

Oncology & Cancer

Study reveals dual role of protein in cancer treatment

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering ...

Oncology & Cancer

Scientists develop potential stealth cancer therapy

Sneaking by cancer's defenses, by disguising tumor-fighting antibodies inside the molecules cancer uses to nourish tumor growth, is the basis of a novel therapy from Yale Cancer Center researchers at the Yale School of Medicine ...

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