(Medical Xpress)—Analyzing genome-wide data from organisms, tissues or cells generates lists of genomic intervals – continuous structures on a genomic sequence, such as a chromosome. An interval's meaning is dependent ...
Scientists have found an experimental small molecule that induces a form of cell death to kill a variety of cancers while enhancing the power of the immune system and leaving healthy cells totally unscathed.
The resistance to cancer treatment is often credited to the heterogenous cellular nature within a tumor. The tumor cell-cell interaction and cell-microenvironment have a key role in the invasion and progression of tumors ...
Pancreatic ductal adenocarcinoma (PDAC) cells maintain a high level of autophagy or degradation, allowing them to thrive in severely limiting microenvironments. However, the process via which autophagy promotes pancreatic ...
A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg-Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new ...
Mar 1, 2021
0
89
In one of the largest studies of its kind, researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival. The team, ...
Apr 10, 2019
0
115
Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer. Their research ...
Mar 23, 2017
1
357
Researchers from the Boston area, Mexico, and Norway have completed a comprehensive genomic analysis of cervical cancer in two patient populations. The study identified recurrent genetic mutations not previously found in ...
Dec 25, 2013
0
0
One subtype of breast cancer shares many genetic features with high-grade serous ovarian cancer, a cancer that is very difficult to treat, according to researchers supported by the National Institutes of Health. The findings ...
Sep 23, 2012
0
0
Researchers at Weill Cornell Medicine have used artificial intelligence to identify drug targets based on mapping regulatory networks in patient tumors. The study, published in Cell Systems, experimentally identified and ...
Sep 5, 2024
0
32
