A new study published in Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein that is overexpressed in several cancer types and promotes tumor progression.
Jan 19, 2024
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Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate cancer treatments, according ...
Jan 18, 2024
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Winning on the battlefield takes a combination of precise intelligence and resolute soldiers. But when it comes to the battle against cancer, the immune system's fighters—the T cells—quickly lose their ability to kill ...
Jan 18, 2024
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Cleveland Clinic researchers have successfully developed a therapeutic peptide that blocks aggressive cancer cells from multiplying rapidly. The results highlight a potential new strategy for developing targeted treatments ...
Jan 17, 2024
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The bacteria Staphylococcus aureus (S. aureus) can worsen the condition of patients with the lymphoma type Sezáry syndrome. A Danish research team has found an underlying mechanism. The improved understanding gives reason ...
Jan 16, 2024
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Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study published January 16 in the open access journal PLOS Biology, by Elena Rainero of the University of Sheffield, ...
Jan 16, 2024
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Cutaneous melanoma is considered the deadliest form of skin cancer because it's aggressive and tends to spread quickly through the body. While scientists have made significant progress in understanding the molecular mechanisms ...
Jan 9, 2024
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Endocrine resistance—a major cause of breast cancer deaths—can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered. The team successfully ...
Jan 9, 2024
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In a paper published in npj Imaging, King's researchers have assessed the use of fertilized chicken eggs as an alternative model that can resolve both ethical and economic issues for preclinical cancer research.
Jan 4, 2024
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Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the German Cancer Research Center (DKFZ) ...
Jan 3, 2024
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