Neuroscience

Lipid epoxides target pain, inflammatory pathways in neurons

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, ...

Medications

Diagnosing intake of two new psychoactive substances

NUS pharmaceutical scientists have developed a systematic approach to understand how the human body manages two new psychoactive substances (NPS) by predicting their biological half-lives and measuring their biological activities ...

Neuroscience

Rethinking the link between cannabinoids and learning

Cannabinoids have a strong influence on how our brains work and how we behave. Many people are only aware of the recreational aspect of cannabinoids. But in fact these molecules naturally exist in our brains where they participate ...

Neuroscience

Cannabinoids decrease the metabolism of glucose in the brain

The nervous system comprises neurons and glial cells (glia means 'glue'). Astrocytes are the most abundant among the glial cells. Among many other functions they undertake to capture glucose from the blood stream to provide ...

Medications

Teen marijuana use boosts risk of adult insomnia

Smoke a lot of weed as a teenager, and when you reach adulthood you'll be more likely to have trouble falling or staying asleep, according to a new University of Colorado Boulder study of nearly 2,000 twins.

Medical research

Curbing your enthusiasm for overeating

Signals between our gut and brain control how and when we eat food. But how the molecular mechanisms involved in this signaling are affected when we eat a high-energy diet and how they contribute to obesity are not well understood.

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