Medical research

Cannabinoids control memory through mitochondria

(Medical Xpress)—Few classes of drugs have galvanized the pharmaceutical industry in recent times like the cannabinoids. This class of molecules includes not only the natural forms, but also a vast new treasury of powerful ...

Neuroscience

Team discovers potential new way to treat anxiety

Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural "endocannabinoids" without gastrointestinal side effects, Vanderbilt University scientists will report next week.

Neuroscience

Lipid epoxides target pain, inflammatory pathways in neurons

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, ...

Neuroscience

Breakthrough discovery in neurotransmission

Samir Haj-Dahmane, Ph.D., senior research scientist at the University at Buffalo Research Institute on Addictions, has discovered how certain neurotransmitters are transported and reach their targets in the brain, which could ...

Medical research

Omega-3 fatty acids fight inflammation via cannabinoids

Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids. A well-known cannabinoid in marijuana, tetrahydrocannabinol, is responsible for some of its ...

Psychology & Psychiatry

Study finds natural chemical helps brain adapt to stress

A natural signaling molecule that activates cannabinoid receptors in the brain plays a critical role in stress-resilience—the ability to adapt to repeated and acute exposures to traumatic stress, according to researchers ...

Neuroscience

Researchers eye potential schizophrenia 'switch'

Researchers at Vanderbilt University Medical Center have discovered a key mechanism that explains how compounds they're developing can suppress schizophrenia-like symptoms in mice without side effects.

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