Medical research

Stem cell advance yields mature heart muscle cells

(Medical Xpress)—A team of University of Wisconsin-Madison researchers has induced human embryonic stem cells (hESC) to differentiate toward pure-population, mature heart muscle cells, or cardiomyocytes. A substrate patterned ...

Cardiology

Improving models to study the human heart

Northwestern Medicine scientists have developed a new method to measure and optimize the maturation process of cultured heart muscle cells, an approach that has the potential to set the future standard for a common cell model ...

Cardiology

Male-female differences in heart disease could start before birth

Males and females differ in prevalence, treatment responses, and survival rates for a variety of diseases. For cardiac disease, women almost uniformly fare far worse than men. There are likely many reasons for this, and scientists ...

Cardiology

Protein dynamics in the beating heart

The protein titin is a large structural component of the sarcomere—the machinery that mediates contraction of cardiac muscle cells. Despite its importance to the beating heart, little is known about titin turnover.

Cardiology

The immune system promotes spontaneous heart regeneration

In adult mammal hearts, cardiomyoctyes do not proliferate following damage such as that caused by myocardial infarction. However, in some mammals, cardiomyocyte proliferation occurs. "Neonatal cardiomyocytes proliferate, ...

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