Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage ...
Cartilage injury is a common cause of joint dysfunction and existing joint prostheses cannot remodel with host joint tissue. However, it is challenging to develop large-scale biomimetic anisotropic constructs that structurally ...
Osteoarthritis (OA) is a debilitating joint disease which affects over 500 million people worldwide, with trends increasing as populations age. OA is caused by progressive, irreversible degeneration of joint cartilage, leading ...
Feb 29, 2024
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About 1 in 7 adults live with degenerative joint disease, also known as osteoarthritis (OA). In recent years, as anterior cruciate ligament (ACL) injury and other joint injuries have become more common among adolescent athletes, ...
Feb 2, 2024
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A lifetime of activity can gradually erode the cartilage that cushions our joints. Someday, we might simply inject a gel to repair it, University of Connecticut researchers report in the Oct. 6 issue of Nature Communications.
Oct 26, 2023
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People suffering with osteoarthritis currently have only two treatment options: pain management and joint surgery. Both options can have complications and neither targets the disease's root causes.
Sep 7, 2023
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A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails. This research, published on ...
Aug 10, 2023
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A previously unstudied protein in the framework of osteoarthritis may be critical in the prevention of the disease, according to groundbreaking new research published in the journal Science Advances, which included work by ...
Aug 7, 2023
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Cartilage is the tissue that protects bones by providing shock absorption and facilitates smooth joint movement. Due to its limited intrinsic healing capacity, stem cell transplantation is a promising therapeutic approach ...
May 3, 2023
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Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.
Apr 22, 2023
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