(Medical Xpress) -- Of the world’s leading causes of death, stroke ranks second – and occurring 8 out of 10 times is ischemic stroke: reduced blood supply to the brain creates a shortage of oxygen, glucose and other ...
In animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by inhibitor of apoptosis proteins (IAPs), guards against excessive cell death. Together these ...
Feb 9, 2023
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When an individual suffers from cancer, the process of programmed cell death called apoptosis does not occur normally, permitting abnormal cells to thrive.
Jan 11, 2022
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Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.
Jun 1, 2022
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Pyroptosis is a highly inflammatory form of programmed necrotic cell death that acts as a defense mechanism against the infection of bacterial and viral pathogens. Pyroptosis is executed by gasdermin, a family of pore-forming ...
Dec 4, 2020
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Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis ...
Sep 13, 2018
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Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer.
Nov 18, 2013
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Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. Caspase inhibitors have therapeutic potential to treat and prevent apoptosis-mediated ...
Sep 9, 2016
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Inflammasomes are assemblies that are central to inflammatory responses. Dr. Lieselotte Vande Walle, Daniel Jiménez Fernández and colleagues from Prof. Mo Lamkanfi's group (VIB/UGent) shed new light on the function of caspase ...
Jun 1, 2016
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