Oncology & Cancer

New model for vascular and tumor research

Two characteristic features of malignant tumours are that they form massive blood vessels and bypass the immune system. A new cell culture technique allows the processes of tumour growth to be studied directly and in real ...

Alzheimer's disease & dementia

'Alzheimer protein' seems to slow down neurotransmitter production

Researchers report how abnormal protein deposits in the brains of Alzheimer's patients disrupt the signaling between nerve cells. They varied the amount of APP protein and related proteins associated with Alzheimer's disease ...

Oncology & Cancer

New mechanism of action for PARP inhibitors discovered

New understanding of how drugs called PARP inhibitors, which have already shown promise for the treatment of women with familial breast and ovarian cancers linked to BRCA mutations, exert their anticancer effects has led ...

Diseases, Conditions, Syndromes

How hepatitis B and delta viruses establish infection of liver cells

Princeton University researchers have developed a new, scalable cell culture system that allows for detailed investigation of how host cells respond to infection with hepatitis B (HBV) and delta virus (HDV). The paper describing ...

Medical research

RNA fragment creates prospect for new atherosclerosis therapies

Atherosclerosis is considered a frequent cause of cardiovascular diseases and strokes. Despite medical progress, case numbers are constantly rising. Targeted new therapeutic approaches are therefore more important than ever.

Oncology & Cancer

Clinical trial hits new target in war on breast cancer

Breast cancers are defined by their drivers – estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer ...

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