Blocking the processes that drive cancer cell growth is at the heart of many new anti-cancer therapies. Unfortunately, after initial success, cancer cells are generally able to develop workarounds to reactivate the pathways ...
May 2, 2019
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A team of international researchers has identified a process that functions like a rheostat to dial up cell division by dislodging a tumor suppressor protein that serves as an off switch. The mechanism offers insight into ...
May 1, 2019
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Disrupting normal circadian rhythms promotes tumor growth and suppresses the effects of a tumor-fighting drug, according to a new study publishing April 30 in the open-access journal PLOS Biology by Yool Lee, Amita Sehgal, ...
Apr 30, 2019
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Normal cells have a complex system of checks and balances that regulate cell division. In cancer, the balance is tipped in favor of cell proliferation. This imbalance arises from increased levels or activity of oncoproteins ...
Apr 29, 2019
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A study by University of North Carolina Lineberger Comprehensive Cancer Center researchers helps explain how tumors recruit blood vessels that provide fuel for their growth as well as an avenue for the tumors to spread.
Apr 19, 2019
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An enzyme involved in cell stress responses could become a new pharmacological target in the treatment of liver cancer, a disease that currently has few available treatment options. The research team at the Centro Nacional ...
Apr 10, 2019
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Although organ failure can be fatal, your kidneys, heart, and liver are prepared for this catastrophe. Emerging research supports the finding that two cell populations quickly respond and work together to restore a non-functioning, ...
Mar 29, 2019
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Children with the severe skin disease, recessive dystrophic epidermolysis bullosa (RDEB), also known as butterfly disease, often develop an aggressive and fatal skin cancer by early adulthood. Now an international team of ...
Mar 7, 2019
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A healthy liver has a significant capacity to regenerate after injury or disease, but little was known about the accompanying detailed changes in cell metabolism. An international research team, that includes scientists from ...
Mar 6, 2019
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Harsh treatments that fail to eliminate tumors can make them more resilient, a new A*STAR study finds. Elevated temperature, nutrient deprivation, or other environmental stressors can cause cancer cells to acquire large-scale ...
Feb 22, 2019
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