Immunotherapy—drug treatment that stimulates the immune system to attack tumors—works well against some types of cancer, but it has shown mixed success against lung cancer.
Feb 2, 2023
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Researchers have discovered a new population of immune cells that are critical in maintaining the immune response against chronic infections and cancer. This population of T cells also mediates the response to immunotherapy ...
Aug 18, 2022
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When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" ...
Jun 28, 2022
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Specially engineered immune cells called CAR T cells have proven themselves to be a powerful weapon against blood cancers, but against solid tumors they are much less effective, due in part to a process called T-cell exhaustion. ...
Dec 2, 2021
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Chimeric antigen receptor (CAR) T-cell therapy is immunotherapy that is making a clinical difference for patients with some blood cancers, solid tumors and chronic viral infections. Scientists at St. Jude Children's Research ...
Nov 17, 2021
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Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.
Jul 19, 2021
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A new UCLA study in zebrafish has identified the process by which air pollution can damage brain cells, potentially contributing to Parkinson's disease.
May 20, 2020
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Amie Lund, a cardiovascular toxicology researcher with the University of North Texas, has found that exposure to certain air pollutants may cause weight gain, especially when coupled with a high-fat diet.
Nov 6, 2019
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Air pollution from diesel engines may worsen allergy-induced lung impairment more when tiny particles are filtered from the exhaust than when they are not, according to new research published online in the American Thoracic ...
Apr 12, 2019
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Researchers at Trinity College Dublin have discovered how lung cell exhaustion affects a patient's ability to fight diseases.
Nov 1, 2018
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