Oncology & Cancer

Targeting telomerase as therapeutic strategy for melanoma

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar ...

Immunology

Disease-fighting antibody production

The influence of environmental cues on the differentiation and function of B cells—white blood cells that produce antibodies as part of humoral immunity—is incompletely understood.

Diseases, Conditions, Syndromes

Oral sirolimus alters the course of DIPNECH syndrome in three patients

Sirolimus, which is used to prevent rejection after kidney transplants, has been used to successfully treat three cases of a rare disorder called diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, or DIPNECH syndrome. ...

Neuroscience

Getting lost—why older people might lose their way

Researchers at the German Center for Neurodegenerative Disease (DZNE) have found a possible explanation for the difficulty in spatial orientation sometimes experienced by elderly people. In the brains of older adults, they ...

Immunology

New way to fight sepsis: Rev up patients' immune systems

While many people have never heard of sepsis, it causes about 250,000 deaths annually in the United States. The condition develops when an infection triggers an overwhelming immune response, ultimately wreaking havoc on the ...

Immunology

Research group discovers a new immune system regulator

Academy Professor Riitta Lahesmaa's research group at Turku and Åbo Akademi University, Finland, has discovered a new regulator of the immune system, a key factor that controls development of regulatory T cells. The discovery ...

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