A machine-learning model has helped scientists discover hundreds of genetic mutations in cancer that are undetectable by current genome sequencing, according to a study published in the journal Science Advances.
Jun 16, 2022
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Cancer biologists are yet to understand the mechanisms and cellular hierarchy leading to the developmental arrest in rhabdomyosarcoma (RMS)—a group of pediatric cancers, which remain enigmatic.
To find new treatment approaches for childhood cancer, scientists at St. Jude Children's Research Hospital are digging deep into disease biology to target a process long considered "undruggable." The approach revealed a new ...
Jul 13, 2022
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About half of prostate cancers have a genetic anomaly that appears to make tumor cells responsive to a new class of cancer-fighting drugs, a new study from the University of Michigan Comprehensive Cancer Center finds.
May 18, 2011
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Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene ...
Dec 22, 2011
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About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Jan 30, 2012
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A new study presents a promising treatment method for so-called fusion-driven cancers, which are currently often difficult to cure. These fusion-driven cancers are caused by an error in cell division that creates a fusion ...
Aug 11, 2023
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When it comes to cancer, developing resistance to therapy and metastasis, the ability to spread outside the organ of origin, are issues of major concern as they give cancer the upper hand.
May 17, 2023
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(Medical Xpress)—A spinal interbody fusion implant with a roughened titanium alloy surface provides an enhanced environment for bone formation, implant stability and fusion compared to one with a smooth titanium alloy surface, ...
Sep 24, 2013
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A new monoclonal antibody has been shown to impede the fusion machinery henipaviruses use to merge with the membrane of cells they are attempting to breach. The antibody halts the attack by blocking membrane fusion and the ...
Sep 30, 2019
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