Despite many developments in the diagnosis and treatment of gastric cancer, it continues to be an important public health problem. Therefore, besides classical methods, new biomolecules are needed to facilitate the prediction ...
Jul 13, 2020
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Science is collaborative by nature, since scientific knowledge only advances, step by step, through combined efforts and findings. Nevertheless, there is often a lack of communication regarding the more technical and everyday ...
Jul 8, 2020
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A new study has created the most comprehensive analysis for understanding how cancer drugs work at a molecular level. Scientists at the Wellcome Sanger Institute, EMBL's European Bioinformatics Institute (EMBL-EBI) and AstraZeneca ...
Jul 7, 2020
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Gene coding regions constitute 2% of the human genome. St. Jude Children's Research Hospital scientists have developed a computational tool to identify alterations that drive tumor formation in the remaining 98% of the genome. ...
Jul 6, 2020
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To inhibit the specific activity of a protein affected by a mutation using high doses of a drug is the usual treatment for many cancers. Except for the first instance in which this strategy is effective, it leads to treatment ...
Jul 1, 2020
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Acute lymphoblastic leukemia (ALL) is the most common kind of cancer in children. T-ALL, a subtype that resembles T-lymphocytes, can be treated successfully with the drug nelarabine. The drug has not been successful, however, ...
Jun 24, 2020
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Genes that perform critical but mundane tasks within cells—such as generating energy or eliminating waste—haven't traditionally been considered prime targets for cancer therapy. A new study led by Caitlin Nichols, Brenton ...
May 25, 2020
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The protein cGAS plays an essential role in cellular innate immunity by detecting the DNA of invading pathogens such as bacteria and viruses, or our own damaged and mislocalized DNA. Activation of the cGAS-STING signaling ...
May 22, 2020
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Recent large-scale efforts to categorize the molecular data of multiple cancer types has yielded so much information that researchers now have a new question: How to turn all this data into meaningful information that guides ...
May 19, 2020
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Cancer biologists at the Mays Cancer Center, home to UT Health San Antonio MD Anderson, have identified important drivers that enable tumors to change their behavior and evade anticancer therapies.
May 18, 2020
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