The secret lives of T cell receptors and their role in the immune response
Canadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components interacts with the cell membrane.
Canadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components interacts with the cell membrane.
Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Oct 10, 2012
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As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.
Feb 2, 2024
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It all sounds similar to a dance event—but are singles or couples dancing here? This was the question Ali Isbilir and Dr. Paolo Annibale at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) ...
Jan 29, 2021
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Regular exposure to cannabis may have a harmful impact on sociability. For some consumers, studies show that it may lead to withdrawal and reduced social interactions. However, the brain network and the mechanisms involved ...
Jul 8, 2020
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Eric Prossnitz, Ph.D., and his team hope to help 93 million obese Americans fight their fat.
Feb 6, 2020
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In preclinical experiments, University of Alabama at Birmingham researchers have revealed a key missing piece of the Alzheimer's disease puzzle. That allowed proof-of-concept experiments—using an existing drug—that dramatically ...
Jan 15, 2020
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Making tiny changes to existing diabetes treatments can alter how they interact with cells, and potentially make the medicines more effective.
Apr 23, 2018
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A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health. Researchers found that ...
Sep 27, 2017
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Cornell University researchers have produced for the first time an image of P2X7, a receptor associated with chronic pain. Visualizing the shape of the receptor has also allowed them to make a second groundbreaking discovery: ...
Apr 14, 2017
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