Lactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis and autoimmune diseases, which is known as the Warburg effect. Despite being an important metabolic ...
Jan 4, 2023
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A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) has discovered that high glucose impairs the anti-tumor activity of immune effector gamma delta T cells (γδ-T cells), which contributes to ...
Nov 29, 2022
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If you gain weight, the fat cells in the body get bigger. So in the extremely obese, those fat cells are greatly enlarged. Now, researchers from the Technical University of Munich (TUM) were able to show how enlarged fat ...
Nov 29, 2022
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The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol consumption. Although ...
Nov 21, 2022
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Over the course of the last several decades, the rate of obesity has progressively increased and is now one of the leading causes of death worldwide—650 million adults are classified as obese. The World Health Organization ...
Nov 21, 2022
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Cancer that splits and develops in new organs around the body becomes significantly more difficult to fight. Now, researchers at Chalmers have shown that these metastatic cancers, that spread from the original, adapt their ...
Nov 17, 2022
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Glucose metabolites (chemicals produced when glucose is broken down by cells), rather than glucose itself, have been discovered to be key to the progression of type 2 diabetes. In diabetes, the pancreatic beta-cells do not ...
Nov 14, 2022
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As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...
Nov 14, 2022
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Tracing the metabolism of tumor cells using magnetic resonance imaging (MRI) has not been feasible in routine clinical settings hitherto. Now, an interdisciplinary research team including the Technical University of Munich ...
Nov 10, 2022
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Reperfusion therapy, including intravenous recombinant tissue plasminogen activator (rtPA) and/or endovascular thrombectomy, is the most effective treatment for ischemic stroke. However, there is uncertainty regarding the ...
Nov 1, 2022
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