Mutations in a protein known to cause Parkinson's Disease derange transportation in and out of brain cells, reports a team of UConn Health researchers in the 27 July issue of Science Signaling. The toxic traffic jams that ...
Sep 15, 2021
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84
Some types of chemotherapy eliminate cancer cells by damaging their DNA. These drugs can also affect healthy cells, where the damage can generate mutations that persist after the end of the treatment.
Sep 14, 2021
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99
Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients. ...
Sep 7, 2021
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15
A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory ...
Sep 2, 2021
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34
Right now, in your body, lurk thousands of cells with DNA mistakes that could cause cancer. Yet only in rare instances do these DNA mistakes, called genetic mutations, lead to a full-blown cancer. Why?
Sep 2, 2021
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129
In the United States, as many as 187,000 people are coping with myelodysplastic syndromes (MDS) that damage the bone marrow's ability to produce healthy blood cells.
Sep 1, 2021
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Talazoparib, a new precision drug, can keep cancer in check in some men with advanced prostate cancer who have run out of options, a phase II clinical trial shows.
Aug 23, 2021
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129
A new study led by University of California, Irvine (UCI) researchers identifies two ways in which APOBEC3A— a vital enzyme that is responsible for genetic changes resulting in a variety of cancers while protecting our ...
Aug 13, 2021
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757
Throughout development, life and the processes of aging, all human cells accumulate mutations, resulting in what is called mosaicism, a condition in which different cells in the same person have different DNA sequences or ...
Aug 13, 2021
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Hypertrophic cardiomyopathy (HCM) is the most common of all genetic heart diseases and is the leading cause of sudden cardiac death. It is characterized by an abnormal thickening of the heart muscle, which over time can lead ...
Aug 12, 2021
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