In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level. Researchers ...
Jul 21, 2020
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147
The most commonly mutated gene in cancer has tantalized scientists for decades about the message of its mutations. Although mutations can occur at more than 1,100 sites within the TP53 gene, they arise with greatest frequency ...
Sep 18, 2018
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37
Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the U.S. in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from ...
Oct 18, 2017
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132
Scientists at the Gladstone Institutes linked a single gene mutation to two types of heart disease: one causes a hole in the heart of infants, and the other causes heart failure. Using cells donated by a family with the mutation, ...
Dec 15, 2016
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47
A common culprit of skin and respiratory infections, Staphylococcus aureus is highly unpredictable. Between 20 and 30 percent of people carry quiet colonies on their skin and in their nostrils, which seldom cause problems ...
May 19, 2022
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85
Solving the genetic puzzle of why babies developed a rare type of diabetes has uncovered a new biological pathway that is fundamental to insulin production, and could boost research into new treatments for more common forms ...
Nov 9, 2020
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As people grow older, certain genetic mutations in hematopoietic stem cells (HSCs)—which give rise to blood and immune cells—can eventually cause cancer or predispose people to cardiovascular disease.
Oct 15, 2020
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53
A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s—with normal cholesterol levels and no other risk factors—to develop coronary artery disease has been identified, ...
Jul 7, 2023
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44
New research has uncovered a surprising role for so-called "jumping" genes that are a source of genetic mutations responsible for a number of human diseases. In the new study from Children's Medical Center Research Institute ...
Apr 8, 2021
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184
Simply put, cancer is caused by mutations to genes within a cell that lead to abnormal cell growth. Finding out what causes that genetic mutation has been the holy grail of medical science for decades. Researchers at the ...
Aug 12, 2015
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