Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could ...
Jan 5, 2021
0
46
A multidisciplinary team of researchers has eliminated fatal mitochondrial DNA mutations in stem cells from patients with mitochondrial diseases. The study is published in a recent online issue of Nature as a collaboration ...
Jul 24, 2015
0
75
Combining structural biology and computation, a Duke-led team of researchers has identified how multiple mutations on the SARS-CoV-2 spike protein independently create variants that are more transmissible and potentially ...
Jun 29, 2021
0
28
In defining the cellular context of diffuse midline gliomas, researchers find the cells fueling their growth and suggest a potential approach to treating them: forcing their cells to be more mature.
Apr 20, 2018
0
86
Two studies in today's Nature Neuroscience, led by researchers at Boston Children's Hospital, Brigham and Women's Hospital (BWH), and Harvard Medical School (HMS), implicate mosaic mutations arising during embryonic development ...
Jan 11, 2021
0
48
A machine-learning model has helped scientists discover hundreds of genetic mutations in cancer that are undetectable by current genome sequencing, according to a study published in the journal Science Advances.
Jun 16, 2022
0
583
Researchers have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder. The answer may allow some children to avoid the risk and expense of bone marrow transplantation, ...
Jul 26, 2018
0
13
Scientists at VCU Massey Cancer Center have identified a protein that operates in tandem with a specific genetic mutation to spur lung cancer growth and could serve as a therapeutic target to treat the disease.
Apr 19, 2021
0
137
Despite smoking's well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs cancer in so-called "never-smokers," ...
Sep 30, 2021
0
75
Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer.
Jul 18, 2018
0
46
