Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery. Now, researchers at Harvard University ...
Feb 2, 2022
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219
A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance ...
Jul 24, 2018
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94
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
After a progressive weakening of the muscles takes away their motor skills, and then their abilities to stand and walk, most males with Duchenne muscular dystrophy die of heart and respiratory failure in their 20s.
Apr 6, 2018
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20
Gene editing is one of the scarier things in the science news, but not all gene editing is the same. It matters whether researchers edit "somatic" cells or "germline" cells.
Mar 18, 2019
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3
Reports show that cancer is the second leading cause of death globally. Scientists from Duke-NUS Medical School have found DNA mutations in some cancers that link them to a bacterial toxin called colibactin. Their findings, ...
Jul 27, 2020
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89
In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one ...
Apr 5, 2021
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84
Researchers at the Stanford University School of Medicine have identified a group of mutations responsible for many cases of a rare immune cell cancer called cutaneous T-cell lymphoma. Identifying the mutations could tip ...
Aug 11, 2015
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90
Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system. Researchers report the molecular details of this process, providing insights into druggable ...
Aug 5, 2019
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46
Gene mutations accumulating in cells are typical of the development of cancer. Finnish researchers have found that a similar accumulation of mutations occurs also in some patients with rheumatoid arthritis.
Jun 21, 2017
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167
