Oncology & Cancer

Measuring cancer cell state can reveal drug susceptibility

Over the past few decades, scientists have made great strides in understanding the genetic mutations that can drive cancer. For some types of cancer, these discoveries have led to the development of drugs that target specific ...

Diseases, Conditions, Syndromes

How Roquin controls the activity of immune cells

Ludwig Maximilians University Munich (LMU) immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

Oncology & Cancer

Young adult cancer patients may need different treatment options

Not all tumors are alike. Young adults who are diagnosed with skin, colon, and other cancer types may require different treatments than older patients receive. That is the primary conclusion of a Mount Sinai study which systematically ...

Genetics

Study encourages cautious approach to CRISPR therapeutics

A comprehensive study—conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups—has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor ...

Neuroscience

New recessive neurodevelopmental disorder identified

The Basson laboratory in the Centre for Craniofacial & Regenerative Biology at King's College London, together with colleagues at UCL GOS Institute of Child Health and University of Milan, have reported a rare neurodevelopmental ...

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